Mal-PEG4-Val-Cit-PAB-PNP 是一种可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。
货号:ajcx33006
CAS:2112738-09-5
分子式:C40H53N7O15
分子量：871.89
溶解度:DMSO : 100 mg/mL (114.69 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.