A mixture that acts as an AhR agonist
货号:ajcx21048
CAS:N/A
分子式:C18H9ClN2O
分子量：304.7
溶解度:DMSO: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

10(11)-Cl-BBQ mixture contains the 10-Cl-BBQ and 11-Cl-BBQ congeners of Cl-BBQ and acts as an aryl hydrocarbon receptor (AhR) agonist.¹It induces transcription of the AhR target cytochrome P450 (CYP) isoformCyp1a1in mouse liver when administered intraperitoneally at a dose of 10 mg/kg. This product is a mixture of 10-Cl-BBQ and 11-Cl-BBQ.

1.Ehrlich, A.K., Pennington, J.M., Bisson, W.H., et al.TCDD, FICZ, and other high affinity AhR ligands dose-dependently determine the fate of CD4+ T cell differentiationToxicol. Sci.161(2)310-320(2018)