AfatinibN-Oxide是Afatinibdimaleate氧化降解过程中的杂质。Afatinibdimaleate是一种不可逆的EGFR家族抑制剂。
货号:ajcx30132
CAS:N/A
分子式:C24H25ClFN5O4
分子量:501.94
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Afatinib N-Oxide is a impurity of Afatinib dimaleate in oxidative degradation. Afatinib dimaleate is an irreversible EGFR family inhibitor[1].
[1]. Pawan kumar, et al. A controlled, efficient and robust process for the synthesis of an epidermal growth factor receptor inhibitor: Afatinib Dimaleate. Chem Rep, 2019, 1(1): 3-12.