DM3 (Maytansinoid DM3) 是一种带有二硫键或硫醇基的美登素类似物,是一种 tubulin 的抑制剂,还是一种抗体-药物偶联物 (ADCs) 的细胞毒性部分。
货号:ajcx29298
CAS:796073-54-6
分子式:C37H52ClN3O10S
分子量:766.34
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs)[1].
[1]. Chen H, et al. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy. Molecules. 2017 Aug 1;22(8).