TargetProtein-bindingmoiety13是一种FKBP的合成配体(SLF),可用于PROTAC合成。
货号:ajcx12898
CAS:1092369-24-8
分子式:C34H44N2O9
分子量:624.72
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Target Protein-binding moiety 13 is a synthetic ligand for FKBP (SLF), which is used in the synthesis of PROTACs.
Target Protein-binding moiety 13 (SLF building block 2) is a synthetic ligand for FKBP (SLF). SLF is composed of only one half of FK506 and it is known to have a significantly weaker affinity for FKBP12.
[1]. Dunyak BM, et al. Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of TwoIntracellular Proteins. ACS Chem Biol. 2015 Nov 20;10(11):2441-7.