EMAC10101d 是一种有效的、选择性的 hCA II 抑制剂，Ki 为 8.1 nM。
货号:ajcx11670
CAS:2561476-24-0
分子式:C17H15Cl2N3O2S2
分子量：428.36
溶解度:DMSO : 62.5 mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range.

参考文献:
[1]. Meleddu R , Distinto S , Cottiglia F , et al. New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII[J]. ACS Medicinal Chemistry Letters, 2020, XXXX(XXX).