Amino-PEG2-NH-Boc 是基于 PEG 的 PROTAC linker，用于合成 PROTAC。
货号:ajcx33228
CAS:127828-22-2
分子式:C9H20N2O3
分子量：204.27
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Amino-PEG2-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Qiu X, et al. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019 May 17;21(10):3838-3841.