28-Epirapamycin是Rapamycin的一种杂质。Rapamycin是一种高效特异的mTOR抑制剂,在HEK293细胞中的IC50为0.1nM。
货号:ajcx29046
CAS:253431-35-5
分子式:C51H79NO13
分子量:914.17
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
28-Epirapamycin is an impurity of Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells[1].
[1]. Edwards SR, et al. The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain. J Biol Chem. 2007;282(18):13395-13401.