MCL-1/BCL-2-IN-2 (Compound 6) 是一种有效的选择性 Mcl-1 和 Bcl-2 抑制剂。
货号:ajcx15638
CAS:2163793-44-8
分子式:C20H15BrN2O2S
分子量:427.31
溶解度:DMSO: 5 mg/mL (11.70 mM; ultrasonic and warming and heat to 60°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
MCL-1/BCL-2-IN-2 (Compound 6) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor[1].
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.