VenetoclaxN-oxide是Venetoclax的杂质。Venetoclax(ABT-199;GDC-0199)是一种高效，选择性的和口服有效的Bcl-2抑制剂，Ki小于0.01nM。
货号:ajcx31644
CAS:N/A
分子式:C45H50ClN7O8S
分子量：884.44
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Venetoclax N-oxide is an impurity of Venetoclax. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM[1].

[1]. Souers AJ, et al. ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets. Nat Med. 2013 Feb;19(2):202-8.