A peptide FPR2 antagonist
货号:ajcx25928
CAS:N/A
分子式:C84H127N24O15 • XCF3COOH
分子量：1713.1
溶解度:DMSO: 5 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PBP 10 is a peptide formyl peptide receptor 2 (FPR2) antagonist (IC₅₀= 60 nM).¹It is active againstE. coli,P. aeruginosa, andS. pneumoniaewhen used at concentrations ranging from 0.1 to 100 µM.²

1.Skovbakke, S.L., Holdfeldt, A., Nielsen, C., et al.Combining elements from two antagonists of formyl peptide receptor 2 generates more potent peptidomimetic antagonistsJ. Med. Chem.60(16)6991-6997(2017) 2.Bucki, R., Pastore, J.J., Randhawa, P., et al.Antibacterial activities of rhodamine B-conjugated gelsolin-derived peptides compared to those of the antimicrobial peptides cathelicidin LL37, magainin II, and melittinAntimicrob. Agents Chemother.48(5)1526-1533(2004)