A major metabolite of eplerenone
货号:ajcx20308
CAS:209253-80-5
分子式:C24H30O7
分子量：430.5
溶解度:Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone .1 It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4.

|1. Cook, C.S., Berry, L.M., Kim, D.H., et al. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: Differential metabolism by CYP3A4 and CYP3A5. Drug Metab. Dispos. 30(12), 1344-1351 (2002).