gp130 agonist; brain penetrant and neuroprotectant
货号:ajcx27702
CAS:339303-87-6
分子式:C15H11FN2S
分子量：270.32
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

gp130 agonist. Protects against NMDA-induced toxicity in primary hippocampal neurons in vitro. Increases STAT3 phosphorylation in SH-SY5Y cells. Brain penetrant.

Alam et al (2018) A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity. ACS Chem.Neurosci. 9 462 PMID:29161500