Positive allosteric modulator of NPY Y4 receptor
货号:ajcx27566
CAS:1942-71-8
分子式:C16H24O2
分子量：248.36
溶解度:24.84mg/ml in DMSO, 24.84mg/ml in Ethanol
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Positive allosteric modulator of neuropeptide Y receptor 4 (Y4R). Potentiates Y4R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC50 values are 0.03, 0.4 and 0.5 nM respectively). Shows selectivity for Y4R over Y1R, Y2R and Y5R.

Schubert et al (2017) Identification and characterization of the first selective Y4 receptor positive allosteric modulator. J.Med.Chem. 60 7605 PMID:28795803