DS44960156 是一种选择性亚甲基四氢叶酸脱氢酶 2 (MTHFD2) 抑制剂，对 MTHFD2 和 MTHFD1 的 IC50 值分别为 1.6 μM 和 >30 μM。
货号:ajcx22380
CAS:2361327-08-2
分子式:C20H15NO5
分子量：349.3
溶解度:DMSO: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：
现货Background:
DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2; IC50= 1.6 µM).1It is selective for MTHFD2 over MTHFD1 (IC50= >30 µM).
1.Kawai, J., Ota, M., Ohki, H., et al.Structure-based design and synthesis of an isozyme-selective MTHFD2 inhibitor with a tricyclic coumarin scaffoldACS Med. Chem. Lett.10(6)893-898(2019)
m.cnreagent.com
