Terminolicacid是一种从Combretumracemosum中分离出的五环三萜糖苷。Terminolicacid可以通过结合IL-1β和IL-6的受体活性位点来抑制促炎细胞因子，并且可以通过结合IL4受体的结合位点来增强抗炎细胞因子。Terminolicacid还表现出中等的抗菌活性。
货号:ajcx31554
CAS:564-13-6
分子式:C30H48O6
分子量：504.7
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum. Terminolic acid can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. Terminolic acid also exhibits moderate antibacterial activity[1][1].

[1]. Gossan DPA, et, al. Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum. Fitoterapia. 2016 Apr;110:89-95. [2]. Legiawati L, et, al. In silico study of Centella asiatica active compounds as anti-inflammatory agent by decreasing Il-1 and Il-6 activity, promoting Il-4 activity. /J. Pharm. Sci. & Res. Vol. 10(9), 2018, 2142-2147.