JNJ-39393406 is an alpha7 nicotinic acetylcholine receptor positive allosteric modulator. JNJ-39393406 plays a key role in inflammatory processes, and is thought to be involved in the pathophysiology of neuropsychiatric diseases, such as schizophrenia and Alzheimer's disease. References: Hashimoto K. Targeting of α7 Nicotinic Acetylcholine Receptors in the Treatment of Schizophrenia and the Use of Auditory Sensory Gating as a Translational Biomarker. Curr Pharm Des. 2015;21(26):3797-806. Review. PubMed PMID: 26044974.
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CAS:953428-73-4