HX-603 is a RXR agonist. HX600 exhibited RXR-selective antagonistic activity. HX603 inhibit the activation of RAR-RXR heterodimers as well as RXR homodimers. References: Zapata-Gonzalez F, Rueda F, Petriz J, Domingo P, Villarroya F, de Madariaga A, Domingo JC. 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development. J Immunol. 2007 May 15;178(10):6130-9. PubMed PMID: 17475839.

纯度：≥98%

CAS：259228-72-3