HMS-I2 is a chemical probe for heterochromatin formation and function. It acts by disrupting of heterochromatin-mediated transcriptional gene silencing. References: Castonguay E, White SA, Kagansky A, St-Cyr DJ, Castillo AG, Brugger C, White R, Bonilla C, Spitzer M, Earnshaw WC, Schalch T, Ekwall K, Tyers M, Allshire RC. Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing. Mol Cell Biol. 2015 Feb;35(4):662-74. doi: 10.1128/MCB.01102-14. Epub 2014 Dec 8. PubMed PMID: 25487573; PubMed Central PMCID: PMC4301722.

纯度：≥98%

CAS：690626-60-9