ST-271 is tyrphostin tyrosine kinase inhibitor. ST271 reduced intracellular Ca2+ levels and inhibited activation of phospholipase C. Elevation of intracellular Ca2+ regulates agonist-induced activation of phospholipase C and that this contributes to the inhibition of thrombin-induced formation of inositol phosphates by the tyrphostin ST271. References: Hjálmarsdóttir MA, Kristinsson KG. Epidemiology of penicillin-non-susceptible pneumococci in Iceland, 1995-2010. J Antimicrob Chemother. 2014 Apr;69(4):940-6. doi: 10.1093/jac/dkt470. Epub 2013 Dec 5. PubMed PMID: 24311742.
纯度:≥98%
CAS:106392-48-7