FR-181157 is a novel prostaglandin (PG) mimetic. FR181157 shows high potency and agonist efficacy at the IP receptor and has good bioavailability. References: Tanaka A, Hattori K, Taniguchi K, Okitsu O, Tabuchi S, Nishio M, Nagakura Y, Maeda N, Murai H, Seki J. Replacing the cyclohexene-linker of FR181157 leading to novel IP receptor agonists: orally active prostacyclin mimetics. Part 6. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4861-4. Epub 2006 Jul 11. PubMed PMID: 16837197.
纯度:≥98%
CAS:171046-15-4