Lifarizine, formerly known as RS-87476, is a calcium and sodium channel antagonist potentially for the treatment of stroke. Lifarizine (RS-87476) showed neuroprotective efficacy in a simplified rat survival model of 2 vessel occlusion. The effects of lifarizine on intracellular Ca2+ and glutamate exocytosis may contribute to its neuroprotective action. References: Spedding M. Reasons why stroke trials underestimate the neuroprotective effects of drugs. Stroke. 2002 Jan;33(1):324-5. PubMed PMID: 11779937.
纯度:≥98%
CAS:119514-66-8