CID2858522, formerly known as ML029, is a potent and selective inhibitor of NF-κB Activation (C50 value of 0.07 μM). CID2858522 specifically inhibits NF-kB activation downstream of protein kinsase C (PKC). CID2858522 may be useful to researchers working in immunology, autoimmune diseases, transplantation and allograft rejection, lymphoid malignancies, immune signaling, and general signal transduction. References: Pu J, Hedrick M, Diaz P, Divlianska D, Peddibhotla M, Hershberger P, Gosalia P, Milewski M, Li L, Brown B, Magnuson G, Roth GP, Sergienko E, Suyama E, Sugarman E, Nguyen K, Mehta A, Vasile S, Su Y, Shi S, Stonich D, Nguyen H, Zeng FY, Novo AM, Vicchiarelli M, Diwan J, Chung TDY, Wimer C, Correa RG, Pinkerton AB, Reed JC. B-cell Specific Inhibitors of NF-κB Activation. 2011 Mar 31 [updated 2011 Nov 21]. Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-. Available from .gov/books/NBK126176/ PubMed PMID: 23469385.

纯度：≥98%

CAS：758679-97-9