CDK5-IN-3 (化合物 11) 是一种有效和选择性的 CDK5 抑制剂，抑制 CDK5/p25 和 CDK2/CycA 的 IC50 值分别为 0.6 nM 和 18 nM。CDK5-IN-3 可用于常染色体显性遗传多囊肾病 （ADPKD） 的研究。
| Cas No. | 2639542-32-6 |
| 分子式 | C22H26N4O |
| 分子量 | 362.47 |
| 溶解度 | DMSO : 10 mg/mL (27.59 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CDK5-IN-3 (compound 11) is a potent and selectiveCDK5inhibitor, withIC50s of 0.6 nM and 18 nM forCDK5/p25andCDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD)[1]. |
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