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GSK-F1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK-F1图片
CAS NO:1402345-92-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
GSK-F1 (Compound F1) 是一种具有口服活性的 PI4KA 抑制剂,对PI4KA、PI4KB、PI3KA、PI3KB、PI3KG 和 PI3KD 的 pIC50 分别为 8.0、5.9、5.8、5.9、5.9 和 6.4。GSK-F1 可用于 HCV 感染的研究。
Cas No.1402345-92-9
分子式C27H18F5N5O4S
分子量603.52
溶解度DMSO : 125 mg/mL (207.12 mM; Need ultrasonic)
储存条件Store at -20°C, sealed storage, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research[1].

[1]. Bojjireddy N, et al. Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels. J Biol Chem. 2014 Feb 28;289(9):6120-32.