Emoxypine Succinate

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Emoxypine Succinate

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

127464-43-1

包装与价格：

包装	价格(元)
1g	电议
5g	电议
10g	电议
25g	电议
100g	电议

产品介绍

Emoxypine succinate 是一种抗氧化剂。 Emoxypine succinate 可用于创伤后的研究。

Cas No.

127464-43-1

别名

美昔得乐琥珀酸盐

分子式

C₁₂H₁₇NO₅

分子量

255.27

储存条件

4°C, away from moisture

General tips

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

产品描述

Emoxypine succinate is anantioxidant. Emoxypine succinate can be used for the research of post-traumatic^[1].

Emoxypine succinate shows reactive oxygen species overproduction and disruption of the mitochondrial inner membrane due to the decreasing of transmembrane potential^[1].

Emoxypine succinate (i.p.; 40 mg/kg; 1 time per day, 14 days) decreases the production of reactive oxygen species, mitochondrial transmembrane potential percentage of leukocyte and the percentage of FITC Annexin V- positive cells of leukocyte suspension^[1].

Animal Model:	Rats^[1]
Dosage:	40 mg/kg
Administration:	Intraperitoneal, 1 time per day, 14 days
Result:	Significantly increased the percentage of Annexin V-positive cells, reduced the apoptotic percentage of white blood cells and decreased the production of reactive oxygen species by leukocytes.

[1]. Krynytska, et al. Features of leukocytes' apoptosis and emoxypine succinate efficacy in case of combined trauma of the chest and both thighs in rats. Bangladesh Journal of Medical Science, (2019). 18(2), 244-251.