| CAS NO: | 1143020-91-0 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 1143020-91-0 |
| Canonical SMILES | O=C(NC1=NC2=C(S1)C=C(S(=O)(CCCN3CCN(CC3)C)=O)C=C2)NC(C4=CC(N5CCOCC5)=CC=C4Cl)=O |
| 分子式 | C27H33ClN6O5S2 |
| 分子量 | 621.2 |
| 溶解度 | 0.1 M HCl: 25 mg/ml,DMSO: 50 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | AZ-GHS-22 is an inverse agonist of the growth hormone secretagogue receptor 1a (GHS-R1a), which is also known as the ghrelin receptor.1It binds to GHS-R1a with an IC50value of 0.77 nM. AZ-GHS-22 decreases food intake in mice by 54% in the first two hours after administration of a 100 mg/kg dose. 1.McCoull, W., Barton, P., Brown, A.J.H., et al.Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonistsJ. Med. Chem.57(14)6128-6140(2014) |
m.cnreagent.com