| CAS NO: | 31005-02-4 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1 g | 电议 |
| Cas No. | 31005-02-4 |
| 别名 | 7-乙氧基香豆素; 7-O-Ethylumbelliferone |
| Canonical SMILES | O=C1C=CC2=CC=C(OCC)C=C2O1 |
| 分子式 | C11H10O3 |
| 分子量 | 190.2 |
| 溶解度 | DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.50 mg/ml,DMSO: 15 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP).1It undergoes O-deethylation by various CYP isoforms, including CYP1A1, -1A2, and -2B in mice and CYP2E1 in humans. 7-Ethoxycoumarin has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea.2,3,4 1.Okamatsu, G., Komatsu, T., Kubota, A., et al.Identification and functional characterization of novel feline cytochrome P450 2AXenobiotica45(6)503-510(2015) 2.Kajbaf, M., Ricci, R., Zambon, S., et al.Contribution of rat intestinal metabolism to the xenobiotics clearanceEur. J. Drug Metab. Pharmacokinet.38(1)33-41(2013) 3.KÖlln, C., and Reichl, S.Cytochrome P450 activity in ex vivo cornea models and a human cornea constructJ. Pharm. Sci.105(7)2204-2212(2016) |
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