您好，欢迎来到化工原料网！ [登录] [免费注册]
化工原料网
发布求购
位置：首页 > 产品库 > Dihydroberberine
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Dihydroberberine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Dihydroberberine图片
CAS NO:483-15-8
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Dihydroberberine 可抑制人类以太相关基因 (hERG) 通道，显着降低热休克蛋白 90 (Hsp90) 的表达及其与 hERG 的相互作用。Dihydroberberine 具有抗炎，抗动脉粥样硬化，降血脂和抗肿瘤活性。
Cas No.483-15-8
别名二氢小檗碱
Canonical SMILESCOC1=CC=C(C=C23)C(CN2CCC(C3=C4)=CC5=C4OCO5)=C1OC
分子式C20H19NO4
分子量337.37
溶解度Soluble in DMSO
储存条件Store at -20°C,sealed storage, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dihydroberberine inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces heat shock protein 90 (Hsp90) expression and its interaction with hERG. Dihydroberberine has anti-inflammatory, anti-atherosclerotic, hypolipidemic and antitumor activities[1].

[1]. Yu D, et al. Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells. PLoS One. 2017 Aug 1;12(8):e0181823.