CAS NO: | 4298-15-1 |
包装: | 1mg |
市场价: | 3765元 |
Cas No. | 4298-15-1 |
别名 | 克尼托喹,Cletoquine? |
Canonical SMILES | ClC1=CC2=C(C=C1)C(NC(C)CCCNCCO)=CC=N2 |
分子式 | C16H22ClN3O |
分子量 | 307.8 |
溶解度 | DMF: soluble,DMSO: soluble,Methanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .1It is formedviathe desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8. 1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018) |