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Desethyl Hydroxychloroquine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Desethyl Hydroxychloroquine图片
CAS NO:4298-15-1
包装:1mg
市场价:3765元

产品介绍
Desethyl Hydroxychloroquine (Desethylhydroxychloroquine) 是 Hydroxychloroquine 的主要活性代谢物。
Cas No.4298-15-1
别名克尼托喹,Cletoquine?
Canonical SMILESClC1=CC2=C(C=C1)C(NC(C)CCCNCCO)=CC=N2
分子式C16H22ClN3O
分子量307.8
溶解度DMF: soluble,DMSO: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine .1It is formedviathe desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.

1.Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8)e4258(2018)