| CAS NO: | 1357920-84-3 |
| 包装 | 价格(元) |
| 2mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 1357920-84-3 |
| 别名 | TSR-011 |
| Canonical SMILES | O=C(NC1=NC2=CC=C(CN3CCC(C(C)(O)C)CC3)C=C2N1[C@H]4CC[C@@H](C(NC(C)C)=O)CC4)C5=CC=C(F)C=C5 |
| 分子式 | C33H44FN5O3 |
| 分子量 | 577.73 |
| 溶解度 | DMSO : ≥ 300 mg/mL (519.27 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase. TSR-011 has antitumour activity in the clinical trials. TSR-011 exerts sustained potent inhibition of ALK-dependent tumour growth in mouse models[1]. References: |
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