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CD73-IN-3
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
CD73-IN-3图片
CAS NO:2375815-63-5
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
CD73-IN-3 是一种有效的 CD73 抑制剂(IC50; Calu6 人细胞实验中)。CD73-IN-3，例 2 源自专利 WO2019168744 A1，具有研究癌症的潜力。
Cas No.2375815-63-5
别名5-[6-甲基-5-[(1S,2R)-2-丙-2-基环丙基]哒嗪-3-基]-1H-嘧啶-2,4-二酮
分子式C15H18N4O2
分子量286.33
溶解度DMSO : 100 mg/mL (349.25 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CD73-IN-3 is a potent CD73 inhibitor (IC50=7.3 nM in Calu6 human cell assay). CD73-IN-3, example 2 extracted from patent WO2019168744 A1, has the potential for cancer research[1].

CD73-IN-3 inhibits CD73 activity in human serum with an EC50 of 0.213 μM. CD73-IN-3 inhibits CD73 activity in human serum by 56.8%, 71.7% and 76.9% at 0.52 μM, 1.56 μM, 4.68 μM,respectively[1].In Calu6 human cell assay against CD73, the IC50 for CD73-IN-3 against CD73 is 0.0073 uM[1].

[1]. Robert Dean Dally, et al. Cd73 inhibitors. Patent WO2019168744 A1.