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CHK-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CHK-IN-1图片
CAS NO:1278405-51-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
CHK-IN-1是一种CHK1和CHK2的抑制剂,具有抗增殖作用。
Cas No.1278405-51-8
Canonical SMILESO=C(C1=NN=C(N[C@@H]2CNCCC2)C3=C1SC(C4=CC=CC(F)=C4)=C3)N.[H]Cl
分子式C18H19ClFN5OS
分子量407.89
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.

CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint[1].

[1]. Novel compounds and therapeutic use thereof for protein kinase inhibition. EP 2477496 A1