产品名称: | 阿匹莫德 |
CAS: | 541550-19-0 |
分子式: | C23H26N6O2 |
分子量: | 418.49 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Inflammation/Immunology |
Target: | IC50: 1 nM (IL-12, human PBMCs), 2 nM (IL-12, monkey PBMCs) |
描述: | Apilimod is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50 of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. |