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Cochlioquinone A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cochlioquinone A图片
CAS NO:32450-25-2
包装与价格:
包装价格(元)
500μg电议
2.5mg电议

产品介绍
Cas No.32450-25-2
Canonical SMILESC[C@]12[C@@](O[C@@H](C(C)(O)C)CC2)([H])CC[C@@]([C@]1([H])[C@@H]3O)(C)OC4=C3C(C=C([C@H](C)[C@H](OC(C)=O)[C@@H](C)CC)C4=O)=O
分子式C30H44O8
分子量532.7
溶解度DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cochlioquinone A, a bioactive compound isolated from D. sacchari and Bipolaris sp., is an inhibitor of diacylglycerol kinase (DGK; Ki = 3.1 µM) and diacylglycerol acyltransferase (DGAT; IC50 = 5.6 µM). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma with an IC50 value of 3 µM. It is also reported to compete with macrophage inflammatory protein-1α for binding to human CCR5 chemokine receptors with an IC50 value of 11 µM.