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N6-Cyclohexyladenosine(CHA)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N6-Cyclohexyladenosine(CHA)图片
CAS NO:36396-99-3
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议

产品介绍
N6-Cyclohexyladenosine (CHA) 是一种选择性 A1 受体激动剂 (EC50 = 8.2 nM)。
Cas No.36396-99-3
别名A1受体促进剂,CHA,CHA
Canonical SMILESOC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NC4CCCCC4)O1)O)O
分子式C16H23N5O4
分子量349.38
溶解度DMSO : ≥ 100 mg/mL (286.22 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2 nM). IC50 value: 8.2 nM (EC50)Target: A1 receptorin vivo: N6-Cyclohexyladenosine exerts anticonvulsant effects and protects against neuronal death. CHA was also found to inhibit the pressor effects of lumbar sympathetic nerve stimulation in rats.

[1]. Asghari AA, et al. Adenosine A1 receptor agonist, N6-cyclohexyladenosine, protects myelin and induces remyelination in an experimental model of rat optic chiasm demyelination; electrophysiological and histopathological studies. J Neurol Sci. 2013 Feb 15;3