化学性质
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 241.29 |
Cas No. | 154235-83-3 |
Formula | C14H15N3O |
Synonyms | CX516; BDP 12; Ampakine CX516 |
Solubility | ≥13.45 mg/mL in DMSO; ≥24.1 mg/mL in H2O with gentle warming; ≥92 mg/mL in EtOH |
Chemical Name | piperidin-1-yl(quinoxalin-6-yl)methanone |
Canonical SMILES | C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2 |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
资料参考
Ampalex (Ampakine CX516) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). Ampalex ameliorates functional deficits in AMPA receptors in a hippocampal slice model of protein accumulation. Researches suggest that AMPA receptors may be potential pharmaceutical targets for the treatment of neurodegenerative diseases, and highlights AMPAkines, in particular, as possible therapeutic agents.