CAS NO: | 37134-80-8 |
包装: | 1mg |
市场价: | 7031元 |
Cas No. | 37134-80-8 |
别名 | 制多巴素 |
Canonical SMILES | O=C(NC[C@@H](N(N=O)O)C(C)C)/C=C/C |
分子式 | C9H17N3O3 |
分子量 | 215.3 |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Dopastin is a bacterial metabolite that has been found inPseudomonasand an inhibitor of dopamine β-hydroxylase (Ki= 4.7 µM).1,2In vivo, dopastin (20 mg/kg) reduces mean systolic blood pressure in spontaneously hypertensive rats. Dopastin also inhibits the germination of barley seeds (IC50= 47 µM).2 1.Iinuma, H., Takeuchi, T., Kondo, S., et al.Dopastin, an inhibitor of dopamine β-hydroxylaseJ. Antibiot. (Tokyo)25(8)497-500(1972) 2.Iinuma, H., Matsuzaki, M., Nagatsu, T., et al.Biochemical and biological studies on dopastin, an inhibitor of dopamine β-hydroxylaseAgric. BioI. Chem.38(11)2107-2111(1974) |