Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
A3692 | OTX-015 | BRD inhibitor | Bromodomain | 202590-98-5 | CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C |
A4093 | ITF2357 (Givinostat) | HDAC inhibitor | HDAC | 732302-99-7 | CCN(CC)CC1=CC2=C(C=C(COC(NC3=CC=C(C(NO)=O)C=C3)=O)C=C2)C=C1.O.Cl |
A4138 | Tofacitinib (CP-690550,Tasocitinib) | Janus kinase inhibitor | JAK | 477600-75-2 | CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N |
A4166 | EPZ5676 | DOT1L inhibitor,potent and SAM competitive | Histone Methyltransferase | 1380288-87-8 | CC(C)N(CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C |
A8708 | Sephin1 | Selective PPP1R15A inhibitor | Protein Ser/Thr Phosphatases | 13098-73-2 | ClC1=CC=CC=C1/C=N/NC(N)=N |
A8712 | MCB-613 | stimulator of steroid receptor coactivator (SRC) | Histone Acetyltransferases | 1162656-22-5 | O=C(/C(CN(CC)C/1)=C/C2=CC=CN=C2)C1=C\C3=CN=CC=C3 |
B1499 | RVX-208 | Potent BET bromodomain inhibitor | Bromodomain | 1044870-39-4 | CC1=CC(=CC(=C1OCCO)C)C2=NC(=O)C3=C(C=C(C=C3N2)OC)OC |
B4891 | ML324 | JMJD2 demethylase inhibitor, potent and cell-permeable | Histone Demethylases | 1222800-79-4 | OC1=CC(C2=CC=C(C(NCCCN(C)C)=C)C=C2)=CC3=CC=CN=C31 |