Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
A3004 | Vemurafenib (PLX4032, RG7204) | BRAF kinase inhibitor | MEK1/2 | 918504-65-1 | CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)C4=CC=C(C=C4)Cl)F |
A3446 | GSK126 | EZH2 inhibitor | EZH2 | 1346574-57-9 | CCC(C)N1C=C(C2=C(C=C(C=C21)C3=CN=C(C=C3)N4CCNCC4)C(=O)NCC5=C(C=C(NC5=O)C)C)C |
A4007 | MLN9708 | Proteasome inhibitor | Proteasome | 1201902-80-8 | B1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)C(CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl |
A4115 | JNJ-7706621 | Potent CDK/Aurora kinase inhibitor | Aurora Kinase | 443797-96-4 | C1=CC(=C(C(=C1)F)C(=O)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F |
A5078 | KU-0063794 | MTORC1 and mTORC2 inhibitor | mTOR | 938440-64-3 | CC1CN(CC(O1)C)C2=NC3=C(C=CC(=N3)C4=CC(=C(C=C4)OC)CO)C(=N2)N5CCOCC5 |
A8169 | Everolimus (RAD001) | MTOR inhibitor | mTOR | 159351-69-6 | OCCO[C@H]1[C@H](OC)C[C@H](C[C@H](C)[C@H](CC([C@H](C)/C=C(C)/[C@@H](O)[C@H]2OC)=O)OC([C@@H]3CCCCN3C(C([C@@]4(O)[C@H](C)CC[C@@H](C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C2=O)O4)=O)=O)=O)CC1 |
A8323 | WP1130 | Deubiquitinase (DUB) inhibitor, Cell permeable | DUB | 856243-80-6 | CCCC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N |
A8547 | Tubastatin A HCl | HDAC6 inhibitor,potent and selective | HDAC | 1310693-92-5 | CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO.Cl |