描述
Gene ID: | 837 | Accession #: | P49662 |
Alternate Names: | Active Human Caspase-4, Active Caspase-4, Caspase-4 Enzyme, Recombinant caspase-4, human caspase-4, human caspases, active caspases. |
Source: | Escherichia Coli. | M.Wt: | N/A |
Appearance: | Lyophilized powder | Storage: | Store at -70℃ |
Formulation: | Lyophilized powder |
Solubility: | Reconstitute to 1 unit per μl in PBS containing 15% glycerol. |
Shipping Condition: | Gel pack. | Handling: | Centrifuge the vial prior to opening. |
Usage: | For Research Use Only! Not to be used in humans. |
资料参考
Caspase-4 is also know as Ich-4 or TX. It belongs to the Caspase-family of cysteine proteases. Caspase-4 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue. Like other Caspases, Caspase-4 exists in cells as an inactive proenzyme. It is matured by proteolysis. The active Caspase-4 is a heterotetramer contain two large and two small subunits. The recombinant active human Caspase-4 was expressed in E. coli. The function of Caspase 4 is believed to be an inflammatory caspase, together with Caspase-1, Caspase-5, with a role in the immune system.