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Fostemsavir Tris
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Fostemsavir Tris图片
CAS NO:864953-39-9
包装与价格：
包装价格(元)
2mg电议
5mg电议

产品介绍
Fostemsavir Tris (BMS-663068 (Tris)) 是HIV-1附着抑制剂。
Cas No.864953-39-9
别名BMS-663068 Tris
Canonical SMILESO=C(N1CCN(C(C2=CC=CC=C2)=O)CC1)C(C3=CN(COP(O)(O)=O)C4=C3C(OC)=CN=C4N5N=C(C)N=C5)=O.OCC(CO)(N)CO
分子式C29H37N8O11P
分子量704.62
溶解度DMSO: 125 mg/mL (177.40 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. HIV-1[1]

Fostemsavir Tris has good antiviral activity in subjects infected with virus shown to be susceptible (IC50,<100 nM) to the agent[1].

[1]. Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56(7):3498-507.