6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine.
| Cas No. | 651055-83-3 |
| Canonical SMILES | NC1=C(C=C(C(F)(F)F)C=C2)C2=C(C=CC=C3)C3=N1 |
| 分子式 | C14H9F3N2 |
| 分子量 | 262.2 |
| 溶解度 | DMSO: soluble,Ethanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine . It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 µM. 6A-8tFP directly competes with protein substrates for the ribosomal active site. |
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