Sulfo-SPDB-DGN462 是ADC的药物连接偶联物。Sulfo-SPDB-DGN462 由毒素分子 DGN462 (HY-101150) 偶联到可裂解的Sulfo-SPDB linker。DGN462 是一种有效的DNA烷基化剂，具有抗肿瘤活性，如急性髓系白血病 (AML)。
| 生物活性 | Sulfo-SPDB-DGN462 is adrug-linker conjugate for ADC. Sulfo-SPDB-DGN462 consists a toxin DGN462 (HY-101150) conjugated to thecleavableSulfo-SPDB linker. DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML)[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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