Valategrast hydrochloride

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

828271-96-1

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议

产品名称

R-411

产品介绍

Valategrast hydrochloride (R-411) 是一种有效的整联蛋白α4β1 (VLA-4)和α4β7双重拮抗剂。Valategrast hydrochloride 可用于慢性阻塞性肺疾病 (COPD) 和哮喘的研究。

生物活性

Valategrast hydrochloride (R-411) is a potentintegrinα4β1 (VLA-4)andα4β7dual antagonist. Valategrast hydrochloride has the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment^[1]^[2].

IC₅₀& Target^[2]

α4β1

α4β7

体外研究
(In Vitro)

Valategrast (hydrochloride) contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS)^[2].

分子量

641.41

Formula

C₃₀H₃₃Cl₄N₃O₄

CAS 号

828271-96-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.