WD2000-012547

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WD2000-012547

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

283172-68-9

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

WD2000-012547 是一种选择性的PARP-1抑制剂，pK_i为 8.221。

生物活性

WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pK_iof 8.221.

IC₅₀& Target^[1]

PARP-1

8.221 (pKi)

体外研究
(In Vitro)

Poly(ADP-ribose) polymerase-1 (PARP-1) functions as a DNA damage sensor and signaling molecule. It plays a vital role in the repair of DNA strand breaks induced by radiation and chemotherapeutic drugs; inhibitors of this enzyme have the potential to improve cancer chemotherapy or radiotherapy. WD2000-012547 (Compound 66) is a representative PARP-1 inhibitor with a pK_iof 8.221^[1].

分子量

262.31

Formula

C₁₇H₁₄N₂O

CAS 号

283172-68-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.