| CAS NO: | 77337-73-6 |
| 包装 | 价格(元) |
| 10mM (in 1mL Water) | 电议 |
| 50mg | 电议 |
| Cas No. | 77337-73-6 |
| 别名 | 阿坎酸钙,Calcium N-acetylhomotaurinate; Campral EC |
| 化学名 | calcium;3-acetamidopropane-1-sulfonate |
| Canonical SMILES | CC(=O)NCCCS(=O)(=O)[O-].CC(=O)NCCCS(=O)(=O)[O-].[Ca+2] |
| 分子式 | C10H20CaN2O8S2 |
| 分子量 | 400.48 |
| 溶解度 | ≥ 40 mg/mL in Water |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction.IC50 value:Target: GABA receptorAcamprosate, or N-acetyl homotaurine, is an N-methyl-D-aspartate receptor modulator approved by the Food and Drug Administration (FDA) as a pharmacological treatment for alcohol dependence.Acamprosate has low bioavailability, but also has an excellent tolerability and safety profile. In comparison with naltrexone and disulfiram, which are the other FDA-approved treatments for alcohol dependence, acamprosate is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so can be administered to patients with hepatitis or liver disease (a common comorbid condition among individuals with alcohol dependence) and to patients who continue drinking alcohol. References: |
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