18号染色体开放阅读框1抗体

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18号染色体开放阅读框1抗体

交货期: 1周
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交货期:	1周
产品别名:	Anti-LDLRAD4 Anti-low density lipoprotein receptor class A domain containing 4 Antibody

产品介绍

靶标：

LDLRAD4

产品别名：

C18orf1； LDLRAD4； low density lipoprotein receptor class A domain containing 4； low density lipoprotein receptor class A domain containing 4； low-density lipoprotein receptor class A domain-containing protein 4； clone 22； 18号染色体开放阅读框1；

背景信息：

Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9 SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。