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PAN3蛋白抗体
PAN3蛋白抗体图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Anti-PAN3
Anti-Poly(A) specific ribonuclease subunit PAN3 Antibody
产品介绍
靶标:

PAN3


产品别名:

CG11486; Dmel\CG11486; PAN3; Poly(A) specific ribonuclease subunit PAN3; Poly(A) specific ribonuclease subunit PAN3; Poly(A) specific ribonuclease subunit PAN3; CG11486-PA; CG11486-PB; CG11486-PC; CG11486-PD; CG11486-PF; CG11486-PG; CG11486-PH; CG11486-PJ; CG11486-PK; CG11486-PL; CG11486-PM; CG11486-PN; CG11486-PO; CG11486-PP; CG11486-PQ; CG11486-PR; PAN3-PA; PAN3-PB; PAN3-PC; PAN3-PD; PAN3-PF; PAN3-PG; PAN3-PH; PAN3-PJ; PAN3-PK; PAN3-PL; PAN3-PM; PAN3-PN; PAN3-PO; PAN3-PP; PAN3-PQ; PAN3-PR; polyA-nuclease related; PAN3蛋白;


背景信息:
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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