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RHOV抗体
产品介绍 靶标： RHOV 产品别名： ARHV； CHP； WRCH2； RHOV； ras homolog family member V； ras homolog family member V； rho-related GTP-binding protein RhoV； CDC42-like GTPase 2； GTP-binding protein-like 2； Rho GTPase-like protein ARHV； WRCH-2； WRCH1-related GTPase； Wnt-1 regulated Cdc42 homolog 2； Wnt-1 responsive Cdc42 homolog 2； ras homolog gene family, member V； 背景信息： The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. Rho V (ras homolog gene family, member V), also known as Rho GTPase-like protein ARHV, CHP or WRCH2 (Wnt-1 responsive Cdc42 homolog 2), is a 236 amino acid protein that controls the actin cytoskeleton through activation of the JNK pathway. A member of the Rho family and small GTPase superfamily, Rho V functions as a lipid anchor at the cytoplasmic side of the cell membrane and is expressed in placenta, pancreas and fetal brain. Rho V is implicated in cell transformation and is encoded by a gene located on human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. 宿主：Rbt |
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